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Home The Nucleus and DNA RNA Proteins Membranes Bioenergetics The Lab         

 

BI 270 CELL BIOLOGY

SPRING 2010

Dr. A.V. LaVerde

Room 459; 216-373-5255

alaverde@ndc.edu

OFFICE HOURS: 

MWF:  9:00 - 9:30,
MW: 12:30 - 1:00;
TR: 1:00 - 2:00

 
Other times by Appointment

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The Nucleus and DNA
RNA
Proteins
Membranes
Bioenergetics
The Lab

              .

 

  Notre Dame College, a Catholic institution in the tradition of the Sisters of Notre Dame,
 educates a diverse population in the liberal arts for personal, professional and global responsibility.

Abridged Syllabus Spring 2010

During the semester, YOUR LEARNING OUTCOMES are to:

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Discuss the evolution of eukaryotic cells and the origin of mitochondria,
flagella and chloroplasts. (I)

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Describe the process of DNA replication and the enzymes involved. (I)

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Discuss RNA transcription and types of post-transcriptional modifications
including the function of spliceosomes.  (II)

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Demonstrate an understanding of the enzymatic function of RNA, including
the role of the telomerase enzyme.  (II)

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Discuss the process of protein synthesis and the role of the molecules involved.  (III)

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Explain the structure of proteins and how the structure correlates with function. (III)

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Describe the nature of the cell membrane and the organelles that make up the eukaryotic endomembrane system.  (IV)

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Explain the Signal Hypothesis and its role in protein transport. (IV)

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Describe the types of membrane junctions between eukaryotic cells.  (V)

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Demonstrate an understanding of bioenergetic pathways, including the Embden- Meyerhoff pathway, the Krebs Cycle and Electron Transport System.  (V)

 

LECTURE TOPICS

TEXT CHAPTER
I. Introduction 1
Viruses & Prokaryotic Cells 1
Eukaryotic cells and their origins 1
II.General nuclear structure 12
Chromosomes: chromatin, nucleosomes, nucleolus 10, 12
The cell cycle and the evolution of mitosis 13, 14, 16
DNA: structure and replication 2, 10, 13, 18
III. RNA: transcription, processing, & functions 2, 18
Controls of gene expression 11, 12
Protein structure and synthesis 2, 11, 12, 18
Enzymes & ribozymes 3, 11, 12
IV. Lipids 2
The cell membrane: structures and functions 4, 16
The endoplasmic reticulum and Golgi complex 8, 18
Coated transport vesicles 7, 8, 15
Lysosomes, microbodies, and peroxisomes 3, 5, 8
V. Microtubules and microfilaments 9
Cellular connections; extracellular environment 7, 16
VI. Carbohydrates & Bioenergetics 2, 3
The Embden Meyerhoff Pathway 3
The mitochondrion, TCA and ETS 5, 18
The chloroplast and photosynthesis 6, 18

v v v v v v v v v v v v v v v v v v v v v v v v

turnbook.gif (1625 bytes)TEXT: Karp, G.  2010.  Cell and Molecular Biology, 6e.

NOTE: ALWAYS bring your TEXT to class !!

 

bulletAdditional readings from scientific journals and web articles may be assigned and discussed in the course.  Scan the journals and the Net for "hot" new info.  

While daily reading assignments will not be made, students should READ relevant material in these chapters.  Journal articles assigned for reading will be on reserve in the library.  Electronic articles, as well as class PowerPoint presentations will be located on MOODLE and on the NDC network at P:\Class Files\BI Courses\TLaV Bio
The instructor's intent is not to cover every fact in the text, but to build a solid foundation of basic environmental concepts.  As we target specific topics in the text,
USE the INDEX to locate these topics.  Use the GLOSSARY to clarify definitions. 

WARNING:
Missing class is hazardous to your grade!

Class attendance is an important part of this course. 
Students can gain up to
25 points for class attendance and participation
There will be FOUR (4) FULL‑PERIOD "quizzes" of 50 points each,
on 2/8
, 2/24, 3/24, and 4/14.  The lowest quiz grade will be dropped
The
Final "Quiz" on or around 5/5 will consist of 50 points on material from Section V (see above), plus 25 points from specific topics in Sections I ‑ IV. 
[
Total points possible 250.] 

             ANY changes in this schedule will be ANNOUNCED.
     Ask your instructor about the BONUS OFFER!

WARNING:
Do NOT wait until the night before

these dates to study!

All "quizzes" will consist of both short answer and essay questions. The questions will deal specifically with material covered and discussed in class. You will be notified of any exception to this format.

There will be several extra credit questions on each quiz.  They will be posted on this  course website.  There will be NO additional extra credit in the course.

It is EXTREMELY important to take GOOD, CLEAR NOTES in class. Using this website, course STUDY GUIDES and POWERPOINTS will be VERY helpful.

NOTE: There are no make‑up quizzes during the semester because
the lowest quiz grade
or a MISSED quiz will be dropped.  If a second quiz is missed for medical or other serious reason, a make‑up exam will be given the week of April 27.  See your Syllabus for further details.

NOTE: While this is a science course, students are held responsible for proper use of the English language to communicate scientific information clearly.

 The sites below will be interesting AND helpful:

Medical Dictionary

The Cell Biology Project

Dictionary of CellBio The Nucleus
Molecular Bio Web Book Cells Alive! (Great animations)
ThinkQuest Cell Bio Cell & Molecular Bio OnLine
KK Bernd @ Davidson CellBio & Links Childs' UAMS CellBio site
Karp's 2e Web Site Cell & Molecular Bio Graphics
Nanoworld (electron microscopy)

Lodish Molecular Bio Site

Markowitz CWRU Site

Netmedicine Search

NIH Biotech Infomation PubMed
Cell (The Journal) New England Journal of Medicine

Nature (The Journal) 

Science (The Journal)

Scirus Search

Ohio Link (search)

Carol Greider Web Site Yahoo Cell Bio
BI 430 Immunology

BI 482 Cancer Seminar

BI110 General Biology NDC BIO Web Site
BI 112 General Biology TLaV Blues Site

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READ THIS NOTICE!!
The instructor considers ACADEMIC DISHONESTY ETHICALLY UNACCEPTABLE
and will NOT tolerate it in ANY form.
See your syllabus or the Student Handbook for further details.

Your education is ultimately your personal responsibility.  Therefore:

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Attend ALL class sessions.

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 Be on time!  Consistent lateness shows a lack of respect for both the instructor and fellow students.

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 Be attentive and participate constructively in each class.  There is no designated nap time during class.

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 Irrelevant chatter is distracting and shows a lack of respect for both the instructor and fellow students.

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The classroom is NOT an appropriate venue for texting!
Cell Phones, Pagers and other devices must be turned OFF during class AND lab.

     The Nucleus and DNA RNA Proteins Membranes Bioenergetics The Lab

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 This page was last updated on 01/15/10.